InsiderFlow

PRLD

Prelude Therapeutics Incorporated$4.35-0.17 (-3.76%)
Prev Close$4.52·MCap$170.5M·P/E·Vol155.7K·Yield

Buys (12M)

3

$25.00M

Sells (12M)

2

$7.6K

Net Activity

Net Buyer

$24.99M

Active Insiders

4

last 12 mo

Over the past 12 months, insider activity at Prelude Therapeutics Incorporated (PRLD) has been dominated by buying, with 3 insider purchases totaling $25.00M and 2 insider sales totaling $7.6K. The most recent insider transaction was by Bonita David P (director, 10 percent owner: ), who purchased $12.50M worth of shares on Apr 23, 2026. Prelude Therapeutics Incorporated operates in the Healthcare sector, within the Biotechnology industry, with a market cap of $170.5M.

PRLD Insider Trading Activity

DateInsiderTypeValue
Apr 23, 2026 Bonita David PBuy$12.50M3.7% OS
Apr 23, 2026 ORBIMED ADVISORS LLCBuy$12.50M3.7% OS
Apr 22, 2026 BAKER BROS. ADVISORS LPBuy$225.232.9% OS
Oct 4, 2025 Huang JaneSell$4.9K
Jul 4, 2025 Huang JaneSell$2.7K
Apr 4, 2025 Huang JaneSell$2.3K
Mar 25, 2025 Combs AndrewBuy$69.3K
Mar 25, 2025 Vaddi KrishnaBuy$467.4K0.9% OS
Mar 20, 2025 Vaddi KrishnaBuy$14.9K
Mar 14, 2025 Vaddi KrishnaBuy$29.5K
Mar 12, 2025 Vaddi KrishnaBuy$69.6K
Jan 3, 2025 Vaddi KrishnaBuy$6.0K
Jan 2, 2025 Vaddi KrishnaBuy$12.0K
Dec 26, 2024 Combs AndrewBuy$85.5K
Dec 20, 2024 Lim Bryant DavidBuy$22.6K
Dec 20, 2024 Vaddi KrishnaBuy$99.3K
May 26, 2023 Vaddi KrishnaBuy$9.8K
May 25, 2023 Chardonnet LaurentBuy$27.5K
May 25, 2023 Lim Bryant DavidBuy$12.9K
May 25, 2023 Vaddi KrishnaBuy$66.7K
May 24, 2023 ORBIMED ADVISORS LLCBuy$5.00M1.1% OS
Apr 6, 2023 Huang JaneSell$81.3K
Dec 21, 2022 Vaddi KrishnaBuy$98.4K
Dec 12, 2022 Chardonnet LaurentBuy$47.6K
Jun 1, 2022 Chardonnet LaurentBuy$42.3K
Dec 17, 2021 Morosini DeborahSell$373.8K
Dec 15, 2021 Combs AndrewBuy$94.9K
Nov 18, 2021 Morosini DeborahSell$456.5K
Oct 6, 2021 Mauro David JSell$464.4K
Sep 9, 2021 Mauro David JSell$550.3K
Sep 7, 2021 Pierce ChristopherSell$708.5K
Aug 30, 2021 Scherle PeggySell$275.8K
Aug 27, 2021 Piper BrianSell$277.8K
Aug 17, 2021 Scherle PeggySell$80.2K
Aug 9, 2021 Mauro David JSell$466.4K
Jul 29, 2021 Scherle PeggySell$709.4K
Jul 8, 2021 Mauro David JSell$412.1K
Jun 9, 2021 Mauro David JSell$486.6K
May 27, 2021 Piper BrianSell$285.5K
May 11, 2021 Scherle PeggySell$408.2K
May 10, 2021 Mauro David JSell$602.1K
Apr 30, 2021 Morosini DeborahSell$129.9K
Apr 30, 2021 Pierce ChristopherSell$132.8K
Apr 29, 2021 Mauro David JSell$884.8K
Apr 21, 2021 Mauro David JSell$772.3K
Apr 15, 2021 Mauro David JSell$368.9K
Apr 15, 2021 Morosini DeborahSell$4.0K
Apr 15, 2021 Pierce ChristopherSell$8.0K
Apr 15, 2021 Scherle PeggySell$177.5K
Apr 9, 2021 Mauro David JSell$605.0K
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PRLD Insider Buying Activity

The following table shows recent insider purchases of Prelude Therapeutics Incorporated (PRLD) stock reported via SEC Form 4 filings.

DateInsiderTypeValue
Apr 23, 2026 Bonita David PBuy$12.50M3.7% OS
Apr 23, 2026 ORBIMED ADVISORS LLCBuy$12.50M3.7% OS
Apr 22, 2026 BAKER BROS. ADVISORS LPBuy$225.232.9% OS
Mar 25, 2025 Combs AndrewBuy$69.3K
Mar 25, 2025 Vaddi KrishnaBuy$467.4K0.9% OS
Mar 20, 2025 Vaddi KrishnaBuy$14.9K
Mar 14, 2025 Vaddi KrishnaBuy$29.5K
Mar 12, 2025 Vaddi KrishnaBuy$69.6K
Jan 3, 2025 Vaddi KrishnaBuy$6.0K
Jan 2, 2025 Vaddi KrishnaBuy$12.0K
Dec 26, 2024 Combs AndrewBuy$85.5K
Dec 20, 2024 Lim Bryant DavidBuy$22.6K
Dec 20, 2024 Vaddi KrishnaBuy$99.3K
May 26, 2023 Vaddi KrishnaBuy$9.8K
May 25, 2023 Chardonnet LaurentBuy$27.5K
May 25, 2023 Lim Bryant DavidBuy$12.9K
May 25, 2023 Vaddi KrishnaBuy$66.7K
May 24, 2023 ORBIMED ADVISORS LLCBuy$5.00M1.1% OS
Dec 21, 2022 Vaddi KrishnaBuy$98.4K
Dec 12, 2022 Chardonnet LaurentBuy$47.6K
Jun 1, 2022 Chardonnet LaurentBuy$42.3K
Dec 15, 2021 Combs AndrewBuy$94.9K

PRLD Insider Selling Activity

The following table shows recent insider sales of Prelude Therapeutics Incorporated (PRLD) stock reported via SEC Form 4 filings.

DateInsiderTypeValue
Oct 4, 2025 Huang JaneSell$4.9K
Jul 4, 2025 Huang JaneSell$2.7K
Apr 4, 2025 Huang JaneSell$2.3K
Apr 6, 2023 Huang JaneSell$81.3K
Dec 17, 2021 Morosini DeborahSell$373.8K
Nov 18, 2021 Morosini DeborahSell$456.5K
Oct 6, 2021 Mauro David JSell$464.4K
Sep 9, 2021 Mauro David JSell$550.3K
Sep 7, 2021 Pierce ChristopherSell$708.5K
Aug 30, 2021 Scherle PeggySell$275.8K
Aug 27, 2021 Piper BrianSell$277.8K
Aug 17, 2021 Scherle PeggySell$80.2K
Aug 9, 2021 Mauro David JSell$466.4K
Jul 29, 2021 Scherle PeggySell$709.4K
Jul 8, 2021 Mauro David JSell$412.1K
Jun 9, 2021 Mauro David JSell$486.6K
May 27, 2021 Piper BrianSell$285.5K
May 11, 2021 Scherle PeggySell$408.2K
May 10, 2021 Mauro David JSell$602.1K
Apr 30, 2021 Morosini DeborahSell$129.9K
Apr 30, 2021 Pierce ChristopherSell$132.8K
Apr 29, 2021 Mauro David JSell$884.8K
Apr 21, 2021 Mauro David JSell$772.3K
Apr 15, 2021 Mauro David JSell$368.9K
Apr 15, 2021 Morosini DeborahSell$4.0K
Apr 15, 2021 Pierce ChristopherSell$8.0K
Apr 15, 2021 Scherle PeggySell$177.5K
Apr 9, 2021 Mauro David JSell$605.0K

PRLD Insiders

Bonita David P

director, 10 percent owner:

Bought $12.50M
1 tradesLast: Apr 23, 2026
ORBIMED ADVISORS LLC

director, 10 percent owner:

Bought $17.50M
2 tradesLast: Apr 23, 2026
BAKER BROS. ADVISORS LP

director, 10 percent owner:

Bought $225.23
1 tradesLast: Apr 22, 2026
Huang Jane

President, CMO

Sold $91.1K
4 tradesLast: Oct 4, 2025
Vaddi Krishna

CEO

Bought $873.7K
10 tradesLast: Mar 25, 2025
Combs Andrew

EVP, Head of Chemistry

Bought $249.7K
3 tradesLast: Mar 25, 2025
Lim Bryant David

CLO, Interim CFO, Corp Sec.

Bought $35.6K
2 tradesLast: Dec 20, 2024
Chardonnet Laurent

Chief Financial Officer

Bought $117.4K
3 tradesLast: May 25, 2023
Morosini Deborah

EVP, Chief of Clinical Affairs

Sold $1.00M
5 tradesLast: Dec 17, 2021
Mauro David J

Chief Medical Officer

Sold $5.61M
10 tradesLast: Oct 6, 2021
Pierce Christopher

EVP and Chief of Business Oper

Sold $882.4K
4 tradesLast: Sep 7, 2021
Scherle Peggy

Chief Scientific Officer

Sold $2.26M
6 tradesLast: Aug 30, 2021
Piper Brian

Chief Financial Officer

Sold $563.4K
2 tradesLast: Aug 27, 2021