InsiderFlow

Vertex Pharmaceuticals Incorporated

$470.20-7.93 (-1.66%)

Prev Close

$478.13

Open

$481.79

High

$486.66

Low

$469.26

Volume

711.0K

Market Cap

$121.44B

P/E

30.69

Div Yield

Over the past 12 months, insider activity at Vertex Pharmaceuticals Incorporated (VRTX) has been exclusively selling, with 0 insider purchases totaling $0.00 and 55 insider sales totaling $180.75M. The most recent insider transaction was by McKechnie Duncan (officer: EVP, Chief Commercial Officer), who sold $1.31M worth of shares on Mar 13, 2026. Vertex Pharmaceuticals Incorporated operates in the Healthcare sector, within the Biotechnology industry, with a market cap of $121.44B.

Buys (12M)

0

$0.00

Sells (12M)

55

$180.75M

Net Activity

Net Seller

$180.75M

Active Insiders

14

last 12 mo

VRTX Price Chart

VRTX Insider Trading Activity

DateInsiderRoleTypeSharesAvg PriceValueShares After
Mar 13, 2026McKechnie Duncanofficer: EVP, Chief Commercial OfficerSell2,633$498.42$1.31M12,489
Mar 6, 2026McKechnie Duncanofficer: EVP, Chief Commercial OfficerSell2,437$475.30$1.16M15,122
Mar 4, 2026Liu Joyofficer: EVP and Chief Legal OfficerSell1,784$495.96$884.8K22,811
Mar 3, 2026Bozic Carmenofficer: EVP and CMOSell2,329$480.31$1.12M37,734
Mar 3, 2026Kewalramani Reshmadirector, officer: CEO & PresidentSell40,000$493.47$19.74M137,878
Mar 2, 2026Ambrose Kristenofficer: SVP & Chief Accounting OfficerSell357$483.36$172.6K6,624
Feb 26, 2026Ambrose Kristenofficer: SVP & Chief Accounting OfficerSell223$486.35$108.5K6,981
Feb 26, 2026Atkinson Edward Morrow IIIofficer: EVP, Chief Technical Ops. Off.Sell668$486.35$324.9K18,432
Feb 26, 2026Biller Jonathanofficer: EVP and Chief Legal OfficerSell945$486.35$459.6K13,659
Feb 26, 2026Bunnage Mark E.officer: EVP, Chief Scientific OfficerSell620$486.35$301.5K7,284
Feb 26, 2026McKechnie Duncanofficer: EVP, Chief Commercial OfficerSell4,910$487.65$2.39M19,969
Feb 26, 2026Sachdev Amitofficer: EVP Chief Patient & Ext Af OffSell1,846$486.35$897.8K55,570
Feb 26, 2026Tatsis Ouraniaofficer: EVP, Chief Reg. & Quality Off.Sell260$486.35$126.5K46,763
Feb 23, 2026Sachdev Amitofficer: EVP Chief Patient & Ext Af OffSell58,613$468.83$27.48M116,627
Feb 19, 2026Ambrose Kristenofficer: SVP & Chief Accounting OfficerSell2,195$484.87$1.06M8,388
Feb 19, 2026Atkinson Edward Morrow IIIofficer: EVP, Chief Technical Ops. Off.Sell7,226$484.68$3.50M21,544
Feb 19, 2026Biller Jonathanofficer: EVP and Chief Legal OfficerSell3,720$484.18$1.80M16,992
Feb 19, 2026Bunnage Mark E.officer: EVP, Chief Scientific OfficerSell3,619$484.31$1.75M9,668
Feb 19, 2026Sachdev AmitEVP Chief Patient & Ext Af OffSell58,613$468.83$27.48M0
Feb 19, 2026Tatsis Ouraniaofficer: EVP, Chief Reg. & Quality Off.Sell977$483.52$472.4K49,018
Feb 18, 2026Bhatia Sangeeta N.directorSell266$500.00$133.0K4,299
Feb 18, 2026Biller Jonathanofficer: EVP and Chief Legal OfficerSell988$499.00$493.0K16,838
Feb 18, 2026Tatsis Ouraniaofficer: EVP, Chief Reg. & Quality Off.Sell1,500$499.99$750.0K46,132
Feb 17, 2026Ambrose KristenSVP & Chief Accounting OfficerSell2,793$484.63$1.35M0
Feb 17, 2026Biller JonathanEVP and Chief Legal OfficerSell5,225$484.06$2.53M0
Feb 17, 2026Bozic CarmenEVP and CMOSell1,912$483.75$924.9K0
Feb 17, 2026Bunnage Mark E.EVP, Chief Scientific OfficerSell4,729$484.18$2.29M0
Feb 17, 2026Kewalramani ReshmaCEO & PresidentSell6,554$483.75$3.17M0
Feb 17, 2026LEIDEN JEFFREY MExecutive ChairmanSell2,964$483.75$1.43M0
Feb 17, 2026McKechnie DuncanEVP, Chief Commercial OfficerSell1,148$483.75$555.3K0
Feb 17, 2026Sachdev AmitEVP Chief Patient & Ext Af OffSell2,140$483.75$1.04M0
Feb 17, 2026Tatsis OuraniaEVP, Chief Reg. & Quality Off.Sell3,271$483.68$1.58M0
Feb 17, 2026WAGNER CHARLES F JREVP, CO & FOSell2,294$483.75$1.11M0
Feb 13, 2026Ambrose KristenSVP & Chief Accounting OfficerSell1,393$487.76$679.5K0
Feb 13, 2026Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off.Sell1,903$487.76$928.2K0
Feb 13, 2026Bhatia Sangeeta N.DirectorSell266$500.00$133.0K0
Feb 13, 2026Biller JonathanEVP and Chief Legal OfficerSell3,981$490.55$1.95M0
Feb 13, 2026Bozic CarmenEVP and CMOSell3,804$487.76$1.86M0
Feb 13, 2026Bunnage Mark E.EVP, Chief Scientific OfficerSell2,283$487.76$1.11M0
Feb 13, 2026Kewalramani ReshmaCEO & PresidentSell13,041$487.76$6.36M0
Feb 13, 2026McKechnie DuncanEVP, Chief Commercial OfficerSell2,283$487.76$1.11M0
Feb 13, 2026Sachdev AmitEVP Chief Patient & Ext Af OffSell3,548$487.76$1.73M0
Feb 13, 2026Tatsis OuraniaEVP, Chief Reg. & Quality Off.Sell5,304$491.22$2.61M0
Feb 13, 2026WAGNER CHARLES F JREVP, CO & FOSell4,565$487.76$2.23M0
Feb 12, 2026Ambrose Kristenofficer: SVP & Chief Accounting OfficerSell1,376$460.43$633.6K10,127
Feb 12, 2026Atkinson Edward Morrow IIIofficer: EVP, Chief Technical Ops. Off.Sell1,751$460.43$806.2K22,046
Feb 12, 2026Biller Jonathanofficer: EVP and Chief Legal OfficerSell1,925$460.43$886.3K20,819
Feb 12, 2026Bunnage Mark E.officer: EVP, Chief Scientific OfficerSell2,021$460.43$930.5K12,914
Feb 12, 2026Tatsis Ouraniaofficer: EVP, Chief Reg. & Quality Off.Sell466$460.43$214.6K51,436
Jan 9, 2026Tatsis Ouraniaofficer: EVP, Chief Reg. & Quality Off.Sell9,000$474.99$4.27M42,293
Jan 8, 2026WAGNER CHARLES F JRofficer: EVP, CO & FOSell19,064$461.00$8.79M37,725
Nov 19, 2025Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off.Sell2,500$434.58$1.09M0
Nov 17, 2025LEIDEN JEFFREY MExecutive ChairmanSell73,292$440.60$32.29M0
May 19, 2025ALTSHULER DAVIDEVP, Chief Scientific OfficerSell52$424.69$22.1K0
May 5, 2025Bhatia Sangeeta N.DirectorSell400$505.86$202.3K0
Mar 12, 2025ALTSHULER DAVIDEVP, Chief Scientific OfficerSell3,231$500.00$1.62M0
Mar 12, 2025WAGNER CHARLES F JREVP & Chief Financial OfficerSell3,298$500.00$1.65M0
Mar 6, 2025Tatsis OuraniaEVP, Chief Reg. & Quality Off.Sell4,058$485.49$1.97M0
Feb 28, 2025Bozic CarmenEVP and CMOSell4,962$479.61$2.38M0
Feb 28, 2025Kewalramani ReshmaCEO & PresidentSell14,079$479.61$6.75M0
Feb 28, 2025Tatsis OuraniaEVP, Chief Reg. & Quality Off.Sell5,492$479.20$2.63M0
Feb 26, 2025ALTSHULER DAVIDEVP, Chief Scientific OfficerSell4,819$482.87$2.33M0
Feb 26, 2025Arbuckle Stuart AEVP, COOSell4,716$483.28$2.28M0
Feb 26, 2025Bozic CarmenEVP and CMOSell3,310$483.28$1.60M0
Feb 26, 2025WAGNER CHARLES F JREVP & Chief Financial OfficerSell3,310$483.28$1.60M0
Feb 19, 2025ALTSHULER DAVIDEVP, Chief Scientific OfficerSell2,293$463.46$1.06M0
Feb 19, 2025Arbuckle Stuart AEVP, COOSell2,724$463.46$1.26M0
Feb 19, 2025Biller JonathanEVP and Chief Legal OfficerSell3,161$459.06$1.45M0
Feb 19, 2025LEIDEN JEFFREY MExecutive ChairmanSell6,066$463.46$2.81M0
Feb 19, 2025Tatsis OuraniaEVP, Chief Reg. & Quality Off.Sell2,537$462.65$1.17M0
Feb 12, 2025ALTSHULER DAVIDEVP, Chief Scientific OfficerSell2,142$467.98$1.00M0
Feb 12, 2025Biller JonathanEVP and Chief Legal OfficerSell5,065$462.48$2.34M0
Feb 12, 2025WAGNER CHARLES F JREVP & Chief Financial OfficerSell2,649$467.98$1.24M0

VRTX Insider Buying Activity

The following table shows recent insider purchases of Vertex Pharmaceuticals Incorporated (VRTX) stock reported via SEC Form 4 filings.

No insider buying activity found for VRTX in the last 12 months.

VRTX Insider Selling Activity

The following table shows recent insider sales of Vertex Pharmaceuticals Incorporated (VRTX) stock reported via SEC Form 4 filings.

DateInsiderRoleTypeSharesAvg PriceValueShares After
Mar 13, 2026McKechnie Duncanofficer: EVP, Chief Commercial OfficerSell2,633$498.42$1.31M12,489
Mar 6, 2026McKechnie Duncanofficer: EVP, Chief Commercial OfficerSell2,437$475.30$1.16M15,122
Mar 4, 2026Liu Joyofficer: EVP and Chief Legal OfficerSell1,784$495.96$884.8K22,811
Mar 3, 2026Bozic Carmenofficer: EVP and CMOSell2,329$480.31$1.12M37,734
Mar 3, 2026Kewalramani Reshmadirector, officer: CEO & PresidentSell40,000$493.47$19.74M137,878
Mar 2, 2026Ambrose Kristenofficer: SVP & Chief Accounting OfficerSell357$483.36$172.6K6,624
Feb 26, 2026Ambrose Kristenofficer: SVP & Chief Accounting OfficerSell223$486.35$108.5K6,981
Feb 26, 2026Atkinson Edward Morrow IIIofficer: EVP, Chief Technical Ops. Off.Sell668$486.35$324.9K18,432
Feb 26, 2026Biller Jonathanofficer: EVP and Chief Legal OfficerSell945$486.35$459.6K13,659
Feb 26, 2026Bunnage Mark E.officer: EVP, Chief Scientific OfficerSell620$486.35$301.5K7,284
Feb 26, 2026McKechnie Duncanofficer: EVP, Chief Commercial OfficerSell4,910$487.65$2.39M19,969
Feb 26, 2026Sachdev Amitofficer: EVP Chief Patient & Ext Af OffSell1,846$486.35$897.8K55,570
Feb 26, 2026Tatsis Ouraniaofficer: EVP, Chief Reg. & Quality Off.Sell260$486.35$126.5K46,763
Feb 23, 2026Sachdev Amitofficer: EVP Chief Patient & Ext Af OffSell58,613$468.83$27.48M116,627
Feb 19, 2026Ambrose Kristenofficer: SVP & Chief Accounting OfficerSell2,195$484.87$1.06M8,388
Feb 19, 2026Atkinson Edward Morrow IIIofficer: EVP, Chief Technical Ops. Off.Sell7,226$484.68$3.50M21,544
Feb 19, 2026Biller Jonathanofficer: EVP and Chief Legal OfficerSell3,720$484.18$1.80M16,992
Feb 19, 2026Bunnage Mark E.officer: EVP, Chief Scientific OfficerSell3,619$484.31$1.75M9,668
Feb 19, 2026Sachdev AmitEVP Chief Patient & Ext Af OffSell58,613$468.83$27.48M0
Feb 19, 2026Tatsis Ouraniaofficer: EVP, Chief Reg. & Quality Off.Sell977$483.52$472.4K49,018
Feb 18, 2026Bhatia Sangeeta N.directorSell266$500.00$133.0K4,299
Feb 18, 2026Biller Jonathanofficer: EVP and Chief Legal OfficerSell988$499.00$493.0K16,838
Feb 18, 2026Tatsis Ouraniaofficer: EVP, Chief Reg. & Quality Off.Sell1,500$499.99$750.0K46,132
Feb 17, 2026Ambrose KristenSVP & Chief Accounting OfficerSell2,793$484.63$1.35M0
Feb 17, 2026Biller JonathanEVP and Chief Legal OfficerSell5,225$484.06$2.53M0
Feb 17, 2026Bozic CarmenEVP and CMOSell1,912$483.75$924.9K0
Feb 17, 2026Bunnage Mark E.EVP, Chief Scientific OfficerSell4,729$484.18$2.29M0
Feb 17, 2026Kewalramani ReshmaCEO & PresidentSell6,554$483.75$3.17M0
Feb 17, 2026LEIDEN JEFFREY MExecutive ChairmanSell2,964$483.75$1.43M0
Feb 17, 2026McKechnie DuncanEVP, Chief Commercial OfficerSell1,148$483.75$555.3K0
Feb 17, 2026Sachdev AmitEVP Chief Patient & Ext Af OffSell2,140$483.75$1.04M0
Feb 17, 2026Tatsis OuraniaEVP, Chief Reg. & Quality Off.Sell3,271$483.68$1.58M0
Feb 17, 2026WAGNER CHARLES F JREVP, CO & FOSell2,294$483.75$1.11M0
Feb 13, 2026Ambrose KristenSVP & Chief Accounting OfficerSell1,393$487.76$679.5K0
Feb 13, 2026Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off.Sell1,903$487.76$928.2K0
Feb 13, 2026Bhatia Sangeeta N.DirectorSell266$500.00$133.0K0
Feb 13, 2026Biller JonathanEVP and Chief Legal OfficerSell3,981$490.55$1.95M0
Feb 13, 2026Bozic CarmenEVP and CMOSell3,804$487.76$1.86M0
Feb 13, 2026Bunnage Mark E.EVP, Chief Scientific OfficerSell2,283$487.76$1.11M0
Feb 13, 2026Kewalramani ReshmaCEO & PresidentSell13,041$487.76$6.36M0
Feb 13, 2026McKechnie DuncanEVP, Chief Commercial OfficerSell2,283$487.76$1.11M0
Feb 13, 2026Sachdev AmitEVP Chief Patient & Ext Af OffSell3,548$487.76$1.73M0
Feb 13, 2026Tatsis OuraniaEVP, Chief Reg. & Quality Off.Sell5,304$491.22$2.61M0
Feb 13, 2026WAGNER CHARLES F JREVP, CO & FOSell4,565$487.76$2.23M0
Feb 12, 2026Ambrose Kristenofficer: SVP & Chief Accounting OfficerSell1,376$460.43$633.6K10,127
Feb 12, 2026Atkinson Edward Morrow IIIofficer: EVP, Chief Technical Ops. Off.Sell1,751$460.43$806.2K22,046
Feb 12, 2026Biller Jonathanofficer: EVP and Chief Legal OfficerSell1,925$460.43$886.3K20,819
Feb 12, 2026Bunnage Mark E.officer: EVP, Chief Scientific OfficerSell2,021$460.43$930.5K12,914
Feb 12, 2026Tatsis Ouraniaofficer: EVP, Chief Reg. & Quality Off.Sell466$460.43$214.6K51,436
Jan 9, 2026Tatsis Ouraniaofficer: EVP, Chief Reg. & Quality Off.Sell9,000$474.99$4.27M42,293
Jan 8, 2026WAGNER CHARLES F JRofficer: EVP, CO & FOSell19,064$461.00$8.79M37,725
Nov 19, 2025Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off.Sell2,500$434.58$1.09M0
Nov 17, 2025LEIDEN JEFFREY MExecutive ChairmanSell73,292$440.60$32.29M0
May 19, 2025ALTSHULER DAVIDEVP, Chief Scientific OfficerSell52$424.69$22.1K0
May 5, 2025Bhatia Sangeeta N.DirectorSell400$505.86$202.3K0
Mar 12, 2025ALTSHULER DAVIDEVP, Chief Scientific OfficerSell3,231$500.00$1.62M0
Mar 12, 2025WAGNER CHARLES F JREVP & Chief Financial OfficerSell3,298$500.00$1.65M0
Mar 6, 2025Tatsis OuraniaEVP, Chief Reg. & Quality Off.Sell4,058$485.49$1.97M0
Feb 28, 2025Bozic CarmenEVP and CMOSell4,962$479.61$2.38M0
Feb 28, 2025Kewalramani ReshmaCEO & PresidentSell14,079$479.61$6.75M0
Feb 28, 2025Tatsis OuraniaEVP, Chief Reg. & Quality Off.Sell5,492$479.20$2.63M0
Feb 26, 2025ALTSHULER DAVIDEVP, Chief Scientific OfficerSell4,819$482.87$2.33M0
Feb 26, 2025Arbuckle Stuart AEVP, COOSell4,716$483.28$2.28M0
Feb 26, 2025Bozic CarmenEVP and CMOSell3,310$483.28$1.60M0
Feb 26, 2025WAGNER CHARLES F JREVP & Chief Financial OfficerSell3,310$483.28$1.60M0
Feb 19, 2025ALTSHULER DAVIDEVP, Chief Scientific OfficerSell2,293$463.46$1.06M0
Feb 19, 2025Arbuckle Stuart AEVP, COOSell2,724$463.46$1.26M0
Feb 19, 2025Biller JonathanEVP and Chief Legal OfficerSell3,161$459.06$1.45M0
Feb 19, 2025LEIDEN JEFFREY MExecutive ChairmanSell6,066$463.46$2.81M0
Feb 19, 2025Tatsis OuraniaEVP, Chief Reg. & Quality Off.Sell2,537$462.65$1.17M0
Feb 12, 2025ALTSHULER DAVIDEVP, Chief Scientific OfficerSell2,142$467.98$1.00M0
Feb 12, 2025Biller JonathanEVP and Chief Legal OfficerSell5,065$462.48$2.34M0
Feb 12, 2025WAGNER CHARLES F JREVP & Chief Financial OfficerSell2,649$467.98$1.24M0

VRTX Insiders

McKechnie Duncan

officer: EVP, Chief Commercial Officer

Sold $4.87M
4 tradesLast: Mar 11, 2026
Liu Joy

officer: EVP and Chief Legal Officer

Sold $884.8K
2 tradesLast: Mar 2, 2026
Bozic Carmen

officer: EVP and CMO

Sold $1.12M
1 tradesLast: Feb 27, 2026
Kewalramani Reshma

director, officer: CEO & President

Sold $19.74M
13 tradesLast: Feb 27, 2026
Ambrose Kristen

officer: SVP & Chief Accounting Officer

Sold $1.98M
5 tradesLast: Feb 26, 2026
Atkinson Edward Morrow III

officer: EVP, Chief Technical Ops. Off.

Sold $2.51M
4 tradesLast: Feb 25, 2026
Biller Jonathan

officer: EVP and Chief Legal Officer

Sold $3.64M
5 tradesLast: Feb 25, 2026
Bunnage Mark E.

officer: EVP, Chief Scientific Officer

Sold $2.98M
4 tradesLast: Feb 25, 2026
Sachdev Amit

officer: EVP Chief Patient & Ext Af Off

Sold $28.38M
9 tradesLast: Feb 25, 2026
Tatsis Ourania

officer: EVP, Chief Reg. & Quality Off.

Sold $3.70M
6 tradesLast: Feb 25, 2026
Sachdev Amit

EVP Chief Patient & Ext Af Off

Sold $30.25M
10 tradesLast: Feb 19, 2026
Ambrose Kristen

SVP & Chief Accounting Officer

Sold $2.03M
4 tradesLast: Feb 18, 2026
Atkinson Edward Morrow III

EVP, Chief Technical Ops. Off.

Sold $4.14M
5 tradesLast: Feb 18, 2026
Biller Jonathan

EVP and Chief Legal Officer

Sold $8.28M
9 tradesLast: Feb 18, 2026
Bunnage Mark E.

EVP, Chief Scientific Officer

Sold $3.40M
4 tradesLast: Feb 18, 2026
LEIDEN JEFFREY M

Executive Chairman

Sold $36.54M
7 tradesLast: Feb 18, 2026
Tatsis Ourania

EVP, Chief Reg. & Quality Off.

Sold $12.10M
11 tradesLast: Feb 18, 2026
Bozic Carmen

EVP and CMO

Sold $6.76M
4 tradesLast: Feb 17, 2026
Kewalramani Reshma

CEO & President

Sold $16.28M
3 tradesLast: Feb 17, 2026
McKechnie Duncan

EVP, Chief Commercial Officer

Sold $1.67M
2 tradesLast: Feb 17, 2026
WAGNER CHARLES F JR

EVP, CO & FO

Sold $7.73M
3 tradesLast: Feb 17, 2026
Bhatia Sangeeta N.

director

Sold $133.0K
1 tradesLast: Feb 13, 2026
Bhatia Sangeeta N.

Director

Sold $335.3K
2 tradesLast: Feb 13, 2026
WAGNER CHARLES F JR

officer: EVP, CO & FO

Sold $4.39M
1 tradesLast: Jan 6, 2026
ALTSHULER DAVID

EVP, Chief Scientific Officer

Sold $6.03M
6 tradesLast: May 15, 2025
Upadhyay Suketu

Director

1 tradesLast: May 1, 2025
WAGNER CHARLES F JR

EVP & Chief Financial Officer

Sold $4.49M
3 tradesLast: Mar 10, 2025
Arbuckle Stuart A

EVP, COO

Sold $3.54M
2 tradesLast: Feb 24, 2025