InsiderFlow

Spyre Therapeutics, Inc.

$40.22-0.19 (-0.47%)

Prev Close

$40.41

Open

$40.92

High

$42.40

Low

$40.21

Volume

369.6K

Market Cap

$2.50B

P/E

Div Yield

Over the past 12 months, insider activity at Spyre Therapeutics, Inc. (SYRE) has been exclusively selling, with 0 insider purchases totaling $0.00 and 9 insider sales totaling $5.16M. The most recent insider transaction was by Burrows Scott L (officer: Chief Financial Officer), who sold $203.2K worth of shares on Mar 3, 2026. Spyre Therapeutics, Inc. operates in the Healthcare sector, within the Biotechnology industry, with a market cap of $2.50B.

Buys (12M)

0

$0.00

Sells (12M)

9

$5.16M

Net Activity

Net Seller

$5.16M

Active Insiders

2

last 12 mo

SYRE Price Chart

SYRE Insider Trading Activity

DateInsiderRoleTypeSharesAvg PriceValueShares After
Mar 3, 2026Burrows Scott Lofficer: Chief Financial OfficerSell5,000$40.65$203.2K98,194
Mar 3, 2026Turtle Camerondirector, officer: Chief Executive OfficerSell30,000$42.19$1.27M651,640
Feb 4, 2026Turtle Camerondirector, officer: Chief Executive OfficerSell15,000$32.80$492.0K671,583
Feb 2, 2026Turtle CameronChief Executive OfficerSell15,000$32.80$492.0K0
Jan 6, 2026Turtle Camerondirector, officer: Chief Executive OfficerSell15,000$30.68$460.1K674,198
Jan 2, 2026Turtle CameronChief Executive OfficerSell15,000$30.68$460.1K0
Dec 1, 2025Turtle CameronChief Executive OfficerSell15,000$29.02$435.4K0
Nov 3, 2025Turtle CameronChief Executive OfficerSell45,000$23.33$1.05M0
Sep 2, 2025Burrows Scott LChief Financial OfficerSell18,428$16.26$299.6K0

SYRE Insider Buying Activity

The following table shows recent insider purchases of Spyre Therapeutics, Inc. (SYRE) stock reported via SEC Form 4 filings.

No insider buying activity found for SYRE in the last 12 months.

SYRE Insider Selling Activity

The following table shows recent insider sales of Spyre Therapeutics, Inc. (SYRE) stock reported via SEC Form 4 filings.

DateInsiderRoleTypeSharesAvg PriceValueShares After
Mar 3, 2026Burrows Scott Lofficer: Chief Financial OfficerSell5,000$40.65$203.2K98,194
Mar 3, 2026Turtle Camerondirector, officer: Chief Executive OfficerSell30,000$42.19$1.27M651,640
Feb 4, 2026Turtle Camerondirector, officer: Chief Executive OfficerSell15,000$32.80$492.0K671,583
Feb 2, 2026Turtle CameronChief Executive OfficerSell15,000$32.80$492.0K0
Jan 6, 2026Turtle Camerondirector, officer: Chief Executive OfficerSell15,000$30.68$460.1K674,198
Jan 2, 2026Turtle CameronChief Executive OfficerSell15,000$30.68$460.1K0
Dec 1, 2025Turtle CameronChief Executive OfficerSell15,000$29.02$435.4K0
Nov 3, 2025Turtle CameronChief Executive OfficerSell45,000$23.33$1.05M0
Sep 2, 2025Burrows Scott LChief Financial OfficerSell18,428$16.26$299.6K0

SYRE Insiders

Burrows Scott L

officer: Chief Financial Officer

Sold $203.2K
4 tradesLast: Mar 3, 2026
Turtle Cameron

director, officer: Chief Executive Officer

Sold $2.22M
9 tradesLast: Mar 2, 2026
Turtle Cameron

Chief Executive Officer

Sold $2.44M
9 tradesLast: Feb 2, 2026
Burrows Scott L

Chief Financial Officer

Sold $299.6K
1 tradesLast: Sep 2, 2025