LYEL

Lyell Immunopharma, Inc.$13.45-0.28 (-2.00%)

Prev Close$13.72·MCap$279.3M·P/E—·Vol75.3K·Yield—

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Buys (12M)

$25.00M

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Sells (12M)

$493.2K

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Net Activity

Net Buyer

$24.51M

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Active Insiders

last 12 mo

Over the past 12 months, insider activity at Lyell Immunopharma, Inc. (LYEL) has been dominated by buying, with 2 insider purchases totaling $25.00M and 19 insider sales totaling $493.2K. The most recent insider transaction was by Shook David (officer: Chief Medical Officer), who sold $25.0K worth of shares on Jun 11, 2026. Lyell Immunopharma, Inc. operates in the Healthcare sector, within the Biotechnology industry, with a market cap of $279.3M.

LYEL Insider Trading Activity

Date	Insider	Role	Type	Shares	Avg Price	Value	Shares After
Jun 11, 2026	Shook David	officer: Chief Medical Officer	Sell	1,977	$12.64	$25.0K	20,923
Mar 9, 2026	ARCH Venture Fund XIII, L.P.	10 percent owner	Buy	488,090	$25.61	$12.50M2.1% OS	1,426,528+52%
Mar 9, 2026	ARCH Venture Partners IX, LLC	10 percent owner	Buy	488,090	$25.61	$12.50M2.1% OS	1,426,528+52%
Feb 11, 2026	Hill Stephen J.	Chief Operating Officer	Sell	1,236	$23.39	$28.9K	0
Feb 11, 2026	Lee Gary K.	Chief Scientific Officer	Sell	1,671	$23.39	$39.1K	0
Feb 11, 2026	Seely Lynn	President and CEO	Sell	7,455	$23.39	$174.4K	0
Feb 10, 2026	Bulis Veronica Sanchez	VP, Corporate Controller	Sell	254	$23.12	$5.9K	0
Feb 9, 2026	Hill Stephen J.	Chief Operating Officer	Sell	109	$23.12	$2.5K	0
Feb 9, 2026	Lee Gary K.	Chief Scientific Officer	Sell	147	$23.12	$3.4K	0
Feb 9, 2026	Seely Lynn	President and CEO	Sell	438	$23.12	$10.1K	0
Dec 24, 2025	Bulis Veronica Sanchez	VP, Corporate Controller	Sell	2,072	$35.80	$74.2K	0
Nov 10, 2025	Bulis Veronica Sanchez	VP, Corporate Controller	Sell	239	$16.10	$3.8K	0
Nov 10, 2025	Hill Stephen J.	Chief Operating Officer	Sell	95	$16.12	$1.5K	0
Nov 10, 2025	Lee Gary K.	Chief Scientific Officer	Sell	138	$16.16	$2.2K	0
Nov 10, 2025	Seely Lynn	President and CEO	Sell	412	$16.11	$6.6K	0
Aug 20, 2025	Hill Stephen J.	Chief Operating Officer	Sell	1,004	$10.54	$10.6K	0
Aug 20, 2025	Newton Charles W.	Chief Financial Officer	Sell	1,453	$10.54	$15.3K	0
Aug 20, 2025	Seely Lynn	President and CEO	Sell	7,257	$10.54	$76.5K	0
Aug 11, 2025	Hill Stephen J.	Chief Operating Officer	Sell	185	$10.43	$1.9K	0
Aug 11, 2025	Lee Gary K.	Chief Scientific Officer	Sell	267	$10.43	$2.8K	0
Aug 11, 2025	Seely Lynn	President and CEO	Sell	797	$10.43	$8.3K	0
Mar 31, 2025	BRAWLEY OTIS W	Director	Buy	35,640	$0.56	$20.0K	0
Mar 21, 2025	Ramachandra Sumant	Director	Buy	200,000	$0.58	$115.2K0.9% OS	0
Mar 17, 2025	Newton Charles W.	Chief Financial Officer	Buy	200,000	$0.56	$111.6K0.9% OS	0
Mar 14, 2025	Klausner Richard	Director	Buy	158,000	$0.60	$94.9K0.7% OS	0
Mar 14, 2025	Seely Lynn	President and CEO	Buy	175,000	$0.61	$106.2K0.8% OS	0
Aug 17, 2023	Klausner Richard	Director	Sell	58,020	$2.28	$132.3K	930,880
Sep 27, 2022	Klausner Richard	Director	Sell	11,100	$6.40	$71.0K	988,900
Jun 23, 2021	FRIEDMAN CATHY	Director	Buy	17,648	$17.00	$300.0K	17,648

LYEL Insider Buying Activity

The following table shows recent insider purchases of Lyell Immunopharma, Inc. (LYEL) stock reported via SEC Form 4 filings.

Date	Insider	Role	Type	Shares	Avg Price	Value	Shares After
Mar 9, 2026	ARCH Venture Fund XIII, L.P.	10 percent owner	Buy	488,090	$25.61	$12.50M2.1% OS	1,426,528+52%
Mar 9, 2026	ARCH Venture Partners IX, LLC	10 percent owner	Buy	488,090	$25.61	$12.50M2.1% OS	1,426,528+52%
Mar 31, 2025	BRAWLEY OTIS W	Director	Buy	35,640	$0.56	$20.0K	0
Mar 21, 2025	Ramachandra Sumant	Director	Buy	200,000	$0.58	$115.2K0.9% OS	0
Mar 17, 2025	Newton Charles W.	Chief Financial Officer	Buy	200,000	$0.56	$111.6K0.9% OS	0
Mar 14, 2025	Klausner Richard	Director	Buy	158,000	$0.60	$94.9K0.7% OS	0
Mar 14, 2025	Seely Lynn	President and CEO	Buy	175,000	$0.61	$106.2K0.8% OS	0
Jun 23, 2021	FRIEDMAN CATHY	Director	Buy	17,648	$17.00	$300.0K	17,648

LYEL Insider Selling Activity

The following table shows recent insider sales of Lyell Immunopharma, Inc. (LYEL) stock reported via SEC Form 4 filings.

Date	Insider	Role	Type	Shares	Avg Price	Value	Shares After
Jun 11, 2026	Shook David	officer: Chief Medical Officer	Sell	1,977	$12.64	$25.0K	20,923
Feb 11, 2026	Hill Stephen J.	Chief Operating Officer	Sell	1,236	$23.39	$28.9K	0
Feb 11, 2026	Lee Gary K.	Chief Scientific Officer	Sell	1,671	$23.39	$39.1K	0
Feb 11, 2026	Seely Lynn	President and CEO	Sell	7,455	$23.39	$174.4K	0
Feb 10, 2026	Bulis Veronica Sanchez	VP, Corporate Controller	Sell	254	$23.12	$5.9K	0
Feb 9, 2026	Hill Stephen J.	Chief Operating Officer	Sell	109	$23.12	$2.5K	0
Feb 9, 2026	Lee Gary K.	Chief Scientific Officer	Sell	147	$23.12	$3.4K	0
Feb 9, 2026	Seely Lynn	President and CEO	Sell	438	$23.12	$10.1K	0
Dec 24, 2025	Bulis Veronica Sanchez	VP, Corporate Controller	Sell	2,072	$35.80	$74.2K	0
Nov 10, 2025	Bulis Veronica Sanchez	VP, Corporate Controller	Sell	239	$16.10	$3.8K	0
Nov 10, 2025	Hill Stephen J.	Chief Operating Officer	Sell	95	$16.12	$1.5K	0
Nov 10, 2025	Lee Gary K.	Chief Scientific Officer	Sell	138	$16.16	$2.2K	0
Nov 10, 2025	Seely Lynn	President and CEO	Sell	412	$16.11	$6.6K	0
Aug 20, 2025	Hill Stephen J.	Chief Operating Officer	Sell	1,004	$10.54	$10.6K	0
Aug 20, 2025	Newton Charles W.	Chief Financial Officer	Sell	1,453	$10.54	$15.3K	0
Aug 20, 2025	Seely Lynn	President and CEO	Sell	7,257	$10.54	$76.5K	0
Aug 11, 2025	Hill Stephen J.	Chief Operating Officer	Sell	185	$10.43	$1.9K	0
Aug 11, 2025	Lee Gary K.	Chief Scientific Officer	Sell	267	$10.43	$2.8K	0
Aug 11, 2025	Seely Lynn	President and CEO	Sell	797	$10.43	$8.3K	0
Aug 17, 2023	Klausner Richard	Director	Sell	58,020	$2.28	$132.3K	930,880
Sep 27, 2022	Klausner Richard	Director	Sell	11,100	$6.40	$71.0K	988,900