LYEL

Healthcare

Lyell Immunopharma, Inc.

$21.26-3.52 (-14.19%)

Prev Close

$24.77

Open

$24.78

High

$25.48

Low

$21.02

Volume

103.1K

Market Cap

$542.1M

P/E

—

Div Yield

—

Over the past 12 months, insider activity at Lyell Immunopharma, Inc. (LYEL) has been dominated by buying, with 7 insider purchases totaling $25.45M and 25 insider sales totaling $824.7K. The most recent insider transaction was by ARCH Venture Fund XIII, L.P. (10 percent owner), who purchased $12.50M worth of shares on Mar 9, 2026. Lyell Immunopharma, Inc. operates in the Healthcare sector, within the Biotechnology industry, with a market cap of $542.1M.

Buys (12M)

$25.45M

Sells (12M)

$824.7K

Net Activity

Net Buyer

$24.62M

Active Insiders

last 12 mo

LYEL Price Chart

LYEL Insider Trading Activity

Date	Insider	Role	Type	Shares	Avg Price	Value	Shares After
Mar 9, 2026↗	ARCH Venture Fund XIII, L.P.	10 percent owner	Buy	488,090	$25.61	$12.50M	1,426,530
Mar 9, 2026↗	ARCH Venture Partners IX, LLC	10 percent owner	Buy	488,090	$25.61	$12.50M	1,426,530
Feb 12, 2026↗	Hill Stephen J.	officer: Chief Operating Officer	Sell	1,236	$23.39	$28.9K	17,795
Feb 12, 2026↗	Lee Gary K.	officer: Chief Scientific Officer	Sell	1,671	$23.39	$39.1K	16,938
Feb 12, 2026↗	Seely Lynn	director, officer: President and CEO	Sell	7,455	$23.39	$174.4K	74,266
Feb 11, 2026↗	Bulis Veronica Sanchez	officer: VP, Corporate Controller	Sell	254	$23.12	$5.9K	15,637
Feb 11, 2026↗	Hill Stephen J.	officer: Chief Operating Officer	Sell	1,345	$23.37	$31.4K	19,031
Feb 11, 2026↗	Lee Gary K.	officer: Chief Scientific Officer	Sell	1,818	$23.37	$42.5K	18,609
Feb 11, 2026↗	Seely Lynn	President and CEO	Sell	7,893	$23.38	$184.5K	81,721
Feb 10, 2026↗	Bulis Veronica Sanchez	VP, Corporate Controller	Sell	254	$23.12	$5.9K	0
Feb 9, 2026↗	Hill Stephen J.	Chief Operating Officer	Sell	109	$23.12	$2.5K	0
Feb 9, 2026↗	Lee Gary K.	Chief Scientific Officer	Sell	147	$23.12	$3.4K	0
Feb 9, 2026↗	Seely Lynn	President and CEO	Sell	438	$23.12	$10.1K	0
Jan 6, 2026↗	Bulis Veronica Sanchez	officer: VP, Corporate Controller	Sell	2,072	$35.80	$74.2K	8,077
Dec 24, 2025↗	Bulis Veronica Sanchez	VP, Corporate Controller	Sell	2,072	$35.80	$74.2K	0
Nov 10, 2025↗	Bulis Veronica Sanchez	VP, Corporate Controller	Sell	239	$16.10	$3.8K	0
Nov 10, 2025↗	Hill Stephen J.	Chief Operating Officer	Sell	95	$16.12	$1.5K	0
Nov 10, 2025↗	Lee Gary K.	Chief Scientific Officer	Sell	138	$16.16	$2.2K	0
Nov 10, 2025↗	Seely Lynn	President and CEO	Sell	412	$16.11	$6.6K	0
Aug 20, 2025↗	Hill Stephen J.	Chief Operating Officer	Sell	1,004	$10.54	$10.6K	0
Aug 20, 2025↗	Lee Gary K.	Chief Scientific Officer	Sell	1,453	$10.54	$15.3K	0
Aug 20, 2025↗	Newton Charles W.	Chief Financial Officer	Sell	1,453	$10.54	$15.3K	0
Aug 20, 2025↗	Seely Lynn	President and CEO	Sell	7,257	$10.54	$76.5K	0
Aug 11, 2025↗	Hill Stephen J.	Chief Operating Officer	Sell	185	$10.43	$1.9K	0
Aug 11, 2025↗	Lee Gary K.	Chief Scientific Officer	Sell	267	$10.43	$2.8K	0
Aug 11, 2025↗	Newton Charles W.	Chief Financial Officer	Sell	267	$10.43	$2.8K	0
Aug 11, 2025↗	Seely Lynn	President and CEO	Sell	797	$10.43	$8.3K	0
Mar 31, 2025↗	BRAWLEY OTIS W	Director	Buy	35,640	$0.56	$20.0K	0
Mar 21, 2025↗	Ramachandra Sumant	Director	Buy	200,000	$0.58	$115.2K	0
Mar 17, 2025↗	Newton Charles W.	Chief Financial Officer	Buy	200,000	$0.56	$111.6K	0
Mar 14, 2025↗	Klausner Richard	Director	Buy	158,000	$0.60	$94.9K	0
Mar 14, 2025↗	Seely Lynn	President and CEO	Buy	175,000	$0.61	$106.2K	0

LYEL Insider Buying Activity

The following table shows recent insider purchases of Lyell Immunopharma, Inc. (LYEL) stock reported via SEC Form 4 filings.

Date	Insider	Role	Type	Shares	Avg Price	Value	Shares After
Mar 9, 2026↗	ARCH Venture Fund XIII, L.P.	10 percent owner	Buy	488,090	$25.61	$12.50M	1,426,530
Mar 9, 2026↗	ARCH Venture Partners IX, LLC	10 percent owner	Buy	488,090	$25.61	$12.50M	1,426,530
Mar 31, 2025↗	BRAWLEY OTIS W	Director	Buy	35,640	$0.56	$20.0K	0
Mar 21, 2025↗	Ramachandra Sumant	Director	Buy	200,000	$0.58	$115.2K	0
Mar 17, 2025↗	Newton Charles W.	Chief Financial Officer	Buy	200,000	$0.56	$111.6K	0
Mar 14, 2025↗	Klausner Richard	Director	Buy	158,000	$0.60	$94.9K	0
Mar 14, 2025↗	Seely Lynn	President and CEO	Buy	175,000	$0.61	$106.2K	0

LYEL Insider Selling Activity

The following table shows recent insider sales of Lyell Immunopharma, Inc. (LYEL) stock reported via SEC Form 4 filings.

Date	Insider	Role	Type	Shares	Avg Price	Value	Shares After
Feb 12, 2026↗	Hill Stephen J.	officer: Chief Operating Officer	Sell	1,236	$23.39	$28.9K	17,795
Feb 12, 2026↗	Lee Gary K.	officer: Chief Scientific Officer	Sell	1,671	$23.39	$39.1K	16,938
Feb 12, 2026↗	Seely Lynn	director, officer: President and CEO	Sell	7,455	$23.39	$174.4K	74,266
Feb 11, 2026↗	Bulis Veronica Sanchez	officer: VP, Corporate Controller	Sell	254	$23.12	$5.9K	15,637
Feb 11, 2026↗	Hill Stephen J.	officer: Chief Operating Officer	Sell	1,345	$23.37	$31.4K	19,031
Feb 11, 2026↗	Lee Gary K.	officer: Chief Scientific Officer	Sell	1,818	$23.37	$42.5K	18,609
Feb 11, 2026↗	Seely Lynn	President and CEO	Sell	7,893	$23.38	$184.5K	81,721
Feb 10, 2026↗	Bulis Veronica Sanchez	VP, Corporate Controller	Sell	254	$23.12	$5.9K	0
Feb 9, 2026↗	Hill Stephen J.	Chief Operating Officer	Sell	109	$23.12	$2.5K	0
Feb 9, 2026↗	Lee Gary K.	Chief Scientific Officer	Sell	147	$23.12	$3.4K	0
Feb 9, 2026↗	Seely Lynn	President and CEO	Sell	438	$23.12	$10.1K	0
Jan 6, 2026↗	Bulis Veronica Sanchez	officer: VP, Corporate Controller	Sell	2,072	$35.80	$74.2K	8,077
Dec 24, 2025↗	Bulis Veronica Sanchez	VP, Corporate Controller	Sell	2,072	$35.80	$74.2K	0
Nov 10, 2025↗	Bulis Veronica Sanchez	VP, Corporate Controller	Sell	239	$16.10	$3.8K	0
Nov 10, 2025↗	Hill Stephen J.	Chief Operating Officer	Sell	95	$16.12	$1.5K	0
Nov 10, 2025↗	Lee Gary K.	Chief Scientific Officer	Sell	138	$16.16	$2.2K	0
Nov 10, 2025↗	Seely Lynn	President and CEO	Sell	412	$16.11	$6.6K	0
Aug 20, 2025↗	Hill Stephen J.	Chief Operating Officer	Sell	1,004	$10.54	$10.6K	0
Aug 20, 2025↗	Lee Gary K.	Chief Scientific Officer	Sell	1,453	$10.54	$15.3K	0
Aug 20, 2025↗	Newton Charles W.	Chief Financial Officer	Sell	1,453	$10.54	$15.3K	0
Aug 20, 2025↗	Seely Lynn	President and CEO	Sell	7,257	$10.54	$76.5K	0
Aug 11, 2025↗	Hill Stephen J.	Chief Operating Officer	Sell	185	$10.43	$1.9K	0
Aug 11, 2025↗	Lee Gary K.	Chief Scientific Officer	Sell	267	$10.43	$2.8K	0
Aug 11, 2025↗	Newton Charles W.	Chief Financial Officer	Sell	267	$10.43	$2.8K	0
Aug 11, 2025↗	Seely Lynn	President and CEO	Sell	797	$10.43	$8.3K	0