LXRX

Lexicon Pharmaceuticals, Inc.$1.67-0.03 (-1.48%)

Prev Close$1.69·MCap$711.8M·P/E—·Vol840.2K·Yield—

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Buys (12M)

$3.12M

▼

Sells (12M)

$0.00

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Net Activity

Net Buyer

$3.12M

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Active Insiders

last 12 mo

Over the past 12 months, insider activity at Lexicon Pharmaceuticals, Inc. (LXRX) has been exclusively buying, with 7 insider purchases totaling $3.12M and 0 insider sales totaling $0.00. The most recent insider transaction was by DEBBANE RAYMOND (director), who purchased $3.0K worth of shares on Feb 27, 2026. Lexicon Pharmaceuticals, Inc. operates in the Healthcare sector, within the Biotechnology industry, with a market cap of $711.8M.

LXRX Insider Trading Activity

Date	Insider	Role	Type	Shares	Avg Price	Value	Shares After
Feb 27, 2026	DEBBANE RAYMOND	director	Buy	2,000	$1.49	$3.0K	1,906,186
Feb 25, 2026	DEBBANE RAYMOND	director	Buy	100,000	$1.47	$147.0K	1,904,186
Feb 23, 2026	DEBBANE RAYMOND	director	Buy	150,000	$1.47	$219.8K	1,804,186
Feb 19, 2026	DEBBANE RAYMOND	Director	Buy	150,000	$1.47	$219.8K	0
Feb 18, 2026	DEBBANE RAYMOND	director	Buy	134,809	$1.31	$176.4K	1,520,498
Feb 13, 2026	DEBBANE RAYMOND	Director	Buy	268,497	$1.31	$352.9K	0
Feb 4, 2026	Invus Global Management, LLC	director, 10 percent owner:	Buy	1,538,462	$1.30	$2.00M	1,538,462
Nov 17, 2023	COATS LONNEL	Chief Executive Officer	Buy	90,000	$1.05	$94.8K	914,359
Nov 14, 2023	Amouyal Philippe	Director	Buy	200,000	$1.01	$201.5K	240,332+496%
Nov 13, 2023	COATS LONNEL	Chief Executive Officer	Buy	10,000	$1.01	$10.1K	824,359
Oct 12, 2023	DEBBANE RAYMOND	Director	Buy	1,000,000	$1.10	$1.10M	1,340,847+293%
Sep 14, 2023	WADE JEFFREY L	President and CFO	Buy	10,000	$1.38	$13.8K	264,341
Aug 7, 2023	McDermott Wendy	VP, Human Resources	Buy	6,000	$1.84	$11.0K	28,478+27%
Jun 29, 2023	COATS LONNEL	Chief Executive Officer	Buy	10,000	$2.16	$21.6K	814,359
Jun 27, 2023	McDermott Wendy	VP, Human Resources	Buy	10,000	$2.43	$24.3K	22,478+80%
Jun 26, 2023	COATS LONNEL	Chief Executive Officer	Buy	20,000	$2.34	$46.7K	804,359
Jun 22, 2023	COATS LONNEL	Chief Executive Officer	Buy	40,000	$2.31	$92.4K	784,359
Jun 20, 2023	WADE JEFFREY L	President and CFO	Buy	12,000	$2.33	$28.0K	254,341
Jun 5, 2023	Artal International S.C.A.	Director	Buy	27,775,050	$2.60	$72.22M6.6% OS	78,634,384+55%
Aug 9, 2022	Artal International S.C.A.	Director	Buy	2,426,070	$2.50	$6.07M0.6% OS	50,859,332
Aug 9, 2022	Invus US Partners LLC	Director	Buy	147,390	$2.50	$368.5K	5,451,204
Aug 1, 2022	Artal International S.C.A.	Director	Buy	16,173,800	$2.50	$40.43M3.8% OS	48,433,260+50%
Aug 1, 2022	Invus US Partners LLC	Director	Buy	982,600	$2.50	$2.46M	5,303,814
Mar 16, 2021	Tessmer James F	VP, Finance & Accounting	Sell	22,912	$6.92	$158.4K	71,766

LXRX Insider Buying Activity

The following table shows recent insider purchases of Lexicon Pharmaceuticals, Inc. (LXRX) stock reported via SEC Form 4 filings.

Date	Insider	Role	Type	Shares	Avg Price	Value	Shares After
Feb 27, 2026	DEBBANE RAYMOND	director	Buy	2,000	$1.49	$3.0K	1,906,186
Feb 25, 2026	DEBBANE RAYMOND	director	Buy	100,000	$1.47	$147.0K	1,904,186
Feb 23, 2026	DEBBANE RAYMOND	director	Buy	150,000	$1.47	$219.8K	1,804,186
Feb 19, 2026	DEBBANE RAYMOND	Director	Buy	150,000	$1.47	$219.8K	0
Feb 18, 2026	DEBBANE RAYMOND	director	Buy	134,809	$1.31	$176.4K	1,520,498
Feb 13, 2026	DEBBANE RAYMOND	Director	Buy	268,497	$1.31	$352.9K	0
Feb 4, 2026	Invus Global Management, LLC	director, 10 percent owner:	Buy	1,538,462	$1.30	$2.00M	1,538,462
Nov 17, 2023	COATS LONNEL	Chief Executive Officer	Buy	90,000	$1.05	$94.8K	914,359
Nov 14, 2023	Amouyal Philippe	Director	Buy	200,000	$1.01	$201.5K	240,332+496%
Nov 13, 2023	COATS LONNEL	Chief Executive Officer	Buy	10,000	$1.01	$10.1K	824,359
Oct 12, 2023	DEBBANE RAYMOND	Director	Buy	1,000,000	$1.10	$1.10M	1,340,847+293%
Sep 14, 2023	WADE JEFFREY L	President and CFO	Buy	10,000	$1.38	$13.8K	264,341
Aug 7, 2023	McDermott Wendy	VP, Human Resources	Buy	6,000	$1.84	$11.0K	28,478+27%
Jun 29, 2023	COATS LONNEL	Chief Executive Officer	Buy	10,000	$2.16	$21.6K	814,359
Jun 27, 2023	McDermott Wendy	VP, Human Resources	Buy	10,000	$2.43	$24.3K	22,478+80%
Jun 26, 2023	COATS LONNEL	Chief Executive Officer	Buy	20,000	$2.34	$46.7K	804,359
Jun 22, 2023	COATS LONNEL	Chief Executive Officer	Buy	40,000	$2.31	$92.4K	784,359
Jun 20, 2023	WADE JEFFREY L	President and CFO	Buy	12,000	$2.33	$28.0K	254,341
Jun 5, 2023	Artal International S.C.A.	Director	Buy	27,775,050	$2.60	$72.22M6.6% OS	78,634,384+55%
Aug 9, 2022	Artal International S.C.A.	Director	Buy	2,426,070	$2.50	$6.07M0.6% OS	50,859,332
Aug 9, 2022	Invus US Partners LLC	Director	Buy	147,390	$2.50	$368.5K	5,451,204
Aug 1, 2022	Artal International S.C.A.	Director	Buy	16,173,800	$2.50	$40.43M3.8% OS	48,433,260+50%
Aug 1, 2022	Invus US Partners LLC	Director	Buy	982,600	$2.50	$2.46M	5,303,814