AMLX
Amylyx Pharmaceuticals, Inc.$28.86+0.00 (—)Prev Close$28.68·MCap$3.62B·P/E—·Vol—·Yield0.03%
▲
Buys (12M)
2
$152.2K
▼
Sells (12M)
26
$13.42M
◆
Net Activity
Net Seller
$13.26M
●
Active Insiders
7
last 12 mo
Over the past 12 months, insider activity at Amylyx Pharmaceuticals, Inc. (AMLX) has been dominated by selling, with 2 insider purchases totaling $152.2K and 26 insider sales totaling $13.42M. The most recent insider transaction was by MILNE GEORGE M JR (director), who sold $830.9K worth of shares on Oct 7, 2026. Amylyx Pharmaceuticals, Inc. operates in the Healthcare sector, within the Biotechnology industry, with a market cap of $3.62B.
AMLX Insider Trading Activity
| Date | Insider | Role | Type | Shares | Avg Price | Value | Shares After |
|---|---|---|---|---|---|---|---|
| Oct 7, 2026 | MILNE GEORGE M JR | director | Sell | 30,000 | $27.70 | $830.9K | 782,881 |
| Sep 14, 2026 | Klee Justin B. | director, officer: Co-Chief Executive Officer | Sell | 30,464 | $32.18 | $980.3K | 3,614,495 |
| Sep 14, 2026 | Cohen Joshua B | director, officer: Co-Chief Executive Officer | Sell | 30,464 | $32.19 | $980.5K | 3,614,042 |
| Sep 14, 2026 | FRATES JAMES M | officer: Chief Financial Officer | Sell | 10,810 | $32.36 | $349.8K | 234,667 |
| Sep 14, 2026 | Mazzariello Gina | officer: Chief Legal Officer | Sell | 9,536 | $32.46 | $309.5K | 190,849 |
| Sep 14, 2026 | Bedrosian Camille L | officer: Chief Medical Officer | Sell | 10,028 | $32.40 | $324.9K | 280,145 |
| Jul 13, 2026 | Mazzariello Gina | officer: Chief Legal Officer | Sell | 30,000 | $17.96 | $538.9K | 194,090 |
| May 26, 2026 | Firestone Karen | director | Buy | 3,800 | $13.51 | $51.3K | 66,900 |
| Feb 25, 2026 | Mazzariello Gina | officer: Chief Legal Officer | Sell | 3,419 | $14.14 | $48.4K | 141,274 |
| Feb 4, 2026 | Cohen Joshua B | director, officer: Co-Chief Executive Officer | Sell | 15,500 | $14.68 | $227.6K | 3,363,965 |
| Feb 4, 2026 | FRATES JAMES M | officer: Chief Financial Officer | Sell | 3,557 | $14.65 | $52.1K | 173,547 |
| Feb 4, 2026 | Klee Justin B. | director, officer: Co-Chief Executive Officer | Sell | 15,500 | $14.69 | $227.6K | 3,363,898 |
| Feb 4, 2026 | Mazzariello Gina | officer: Chief Legal Officer | Sell | 3,448 | $14.65 | $50.5K | 144,693 |
| Feb 2, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 15,500 | $14.68 | $227.6K | 0 |
| Feb 2, 2026 | FRATES JAMES M | Chief Financial Officer | Sell | 3,557 | $14.65 | $52.1K | 0 |
| Feb 2, 2026 | Klee Justin B. | Co-Chief Executive Officer | Sell | 15,500 | $14.69 | $227.6K | 0 |
| Feb 2, 2026 | Mazzariello Gina | Chief Legal Officer | Sell | 3,448 | $14.65 | $50.5K | 0 |
| Jan 20, 2026 | Cohen Joshua B | director, officer: Co-Chief Executive Officer | Sell | 138,167 | $13.59 | $1.88M | 3,379,465 |
| Jan 20, 2026 | Klee Justin B. | director, officer: Co-Chief Executive Officer | Sell | 138,188 | $13.59 | $1.88M | 3,379,398 |
| Jan 15, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 138,167 | $13.59 | $1.88M | 0 |
| Jan 15, 2026 | Klee Justin B. | Co-Chief Executive Officer | Sell | 138,188 | $13.59 | $1.88M | 0 |
| Jan 8, 2026 | Cohen Joshua B | director, officer: Co-Chief Executive Officer | Sell | 7,715 | $11.09 | $85.6K | 3,317,632 |
| Jan 8, 2026 | FRATES JAMES M | officer: Chief Financial Officer | Sell | 3,326 | $11.11 | $37.0K | 177,104 |
| Jan 8, 2026 | Klee Justin B. | director, officer: Co-Chief Executive Officer | Sell | 7,715 | $11.09 | $85.6K | 3,317,586 |
| Jan 6, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 7,715 | $11.09 | $85.6K | 0 |
| Jan 6, 2026 | FRATES JAMES M | Chief Financial Officer | Sell | 3,326 | $11.11 | $37.0K | 0 |
| Dec 23, 2025 | Firestone Karen | Director | Buy | 8,100 | $12.45 | $100.8K | 0 |
| Dec 1, 2025 | Bedrosian Camille L | Chief Medical Officer | Sell | 6,580 | $14.35 | $94.4K | 0 |
| Sep 30, 2025 | Bedrosian Camille L | Chief Medical Officer | Sell | 12,039 | $14.58 | $175.5K | 0 |
| Sep 30, 2025 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 29,933 | $14.35 | $429.5K | 0 |
| Sep 30, 2025 | FRATES JAMES M | Chief Financial Officer | Sell | 10,558 | $14.65 | $154.7K | 0 |
| Sep 30, 2025 | Klee Justin B. | Co-Chief Executive Officer | Sell | 29,975 | $14.38 | $431.0K | 0 |
| Sep 30, 2025 | Mazzariello Gina | Chief Legal Officer | Sell | 8,828 | $14.58 | $128.7K | 0 |
| Aug 12, 2025 | Mazzariello Gina | Chief Legal Officer | Sell | 30,000 | $8.20 | $246.1K | 0 |
| Mar 31, 2025 | Bedrosian Camille L | Chief Medical Officer | Sell | 12,425 | $3.47 | $43.1K | 0 |
| Mar 31, 2025 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 21,490 | $3.47 | $74.5K | 0 |
| Mar 31, 2025 | FRATES JAMES M | Chief Financial Officer | Sell | 10,896 | $3.47 | $37.8K | 0 |
| Mar 31, 2025 | Klee Justin B. | Co-Chief Executive Officer | Sell | 21,490 | $3.46 | $74.5K | 0 |
| Mar 31, 2025 | Mazzariello Gina | Chief Legal Officer | Sell | 9,192 | $3.48 | $32.0K | 0 |
| Mar 20, 2025 | Zeiher Bernhardt G | Director | Buy | 10,000 | $3.70 | $37.0K | 0 |
| Mar 3, 2025 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 4,595 | $3.17 | $14.5K | 0 |
| Mar 3, 2025 | Klee Justin B. | Co-Chief Executive Officer | Sell | 4,595 | $3.15 | $14.5K | 0 |
| Mar 3, 2025 | Mazzariello Gina | Chief Legal Officer | Sell | 1,611 | $3.12 | $5.0K | 0 |
| Feb 24, 2025 | Mazzariello Gina | Chief Legal Officer | Sell | 4,169 | $3.15 | $13.1K | 0 |
| Feb 3, 2025 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 11,851 | $3.47 | $41.1K | 0 |
| Feb 3, 2025 | Klee Justin B. | Co-Chief Executive Officer | Sell | 11,855 | $3.47 | $41.1K | 0 |
| Feb 3, 2025 | Mazzariello Gina | Chief Legal Officer | Sell | 3,678 | $3.49 | $12.8K | 0 |
| Jan 6, 2025 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 7,471 | $4.05 | $30.2K | 0 |
| Jan 6, 2025 | Klee Justin B. | Co-Chief Executive Officer | Sell | 7,471 | $4.04 | $30.2K | 0 |
| Dec 2, 2024 | Bedrosian Camille L | Chief Medical Officer | Sell | 5,421 | $5.54 | $30.0K | 0 |
Showing 1–50 of 86
1 / 2
AMLX Insider Buying Activity
The following table shows recent insider purchases of Amylyx Pharmaceuticals, Inc. (AMLX) stock reported via SEC Form 4 filings.
| Date | Insider | Role | Type | Shares | Avg Price | Value | Shares After |
|---|---|---|---|---|---|---|---|
| May 26, 2026 | Firestone Karen | director | Buy | 3,800 | $13.51 | $51.3K | 66,900 |
| Dec 23, 2025 | Firestone Karen | Director | Buy | 8,100 | $12.45 | $100.8K | 0 |
| Mar 20, 2025 | Zeiher Bernhardt G | Director | Buy | 10,000 | $3.70 | $37.0K | 0 |
AMLX Insider Selling Activity
The following table shows recent insider sales of Amylyx Pharmaceuticals, Inc. (AMLX) stock reported via SEC Form 4 filings.
| Date | Insider | Role | Type | Shares | Avg Price | Value | Shares After |
|---|---|---|---|---|---|---|---|
| Oct 7, 2026 | MILNE GEORGE M JR | director | Sell | 30,000 | $27.70 | $830.9K | 782,881 |
| Sep 14, 2026 | Klee Justin B. | director, officer: Co-Chief Executive Officer | Sell | 30,464 | $32.18 | $980.3K | 3,614,495 |
| Sep 14, 2026 | Cohen Joshua B | director, officer: Co-Chief Executive Officer | Sell | 30,464 | $32.19 | $980.5K | 3,614,042 |
| Sep 14, 2026 | FRATES JAMES M | officer: Chief Financial Officer | Sell | 10,810 | $32.36 | $349.8K | 234,667 |
| Sep 14, 2026 | Mazzariello Gina | officer: Chief Legal Officer | Sell | 9,536 | $32.46 | $309.5K | 190,849 |
| Sep 14, 2026 | Bedrosian Camille L | officer: Chief Medical Officer | Sell | 10,028 | $32.40 | $324.9K | 280,145 |
| Jul 13, 2026 | Mazzariello Gina | officer: Chief Legal Officer | Sell | 30,000 | $17.96 | $538.9K | 194,090 |
| Feb 25, 2026 | Mazzariello Gina | officer: Chief Legal Officer | Sell | 3,419 | $14.14 | $48.4K | 141,274 |
| Feb 4, 2026 | Cohen Joshua B | director, officer: Co-Chief Executive Officer | Sell | 15,500 | $14.68 | $227.6K | 3,363,965 |
| Feb 4, 2026 | FRATES JAMES M | officer: Chief Financial Officer | Sell | 3,557 | $14.65 | $52.1K | 173,547 |
| Feb 4, 2026 | Klee Justin B. | director, officer: Co-Chief Executive Officer | Sell | 15,500 | $14.69 | $227.6K | 3,363,898 |
| Feb 4, 2026 | Mazzariello Gina | officer: Chief Legal Officer | Sell | 3,448 | $14.65 | $50.5K | 144,693 |
| Feb 2, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 15,500 | $14.68 | $227.6K | 0 |
| Feb 2, 2026 | FRATES JAMES M | Chief Financial Officer | Sell | 3,557 | $14.65 | $52.1K | 0 |
| Feb 2, 2026 | Klee Justin B. | Co-Chief Executive Officer | Sell | 15,500 | $14.69 | $227.6K | 0 |
| Feb 2, 2026 | Mazzariello Gina | Chief Legal Officer | Sell | 3,448 | $14.65 | $50.5K | 0 |
| Jan 20, 2026 | Cohen Joshua B | director, officer: Co-Chief Executive Officer | Sell | 138,167 | $13.59 | $1.88M | 3,379,465 |
| Jan 20, 2026 | Klee Justin B. | director, officer: Co-Chief Executive Officer | Sell | 138,188 | $13.59 | $1.88M | 3,379,398 |
| Jan 15, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 138,167 | $13.59 | $1.88M | 0 |
| Jan 15, 2026 | Klee Justin B. | Co-Chief Executive Officer | Sell | 138,188 | $13.59 | $1.88M | 0 |
| Jan 8, 2026 | Cohen Joshua B | director, officer: Co-Chief Executive Officer | Sell | 7,715 | $11.09 | $85.6K | 3,317,632 |
| Jan 8, 2026 | FRATES JAMES M | officer: Chief Financial Officer | Sell | 3,326 | $11.11 | $37.0K | 177,104 |
| Jan 8, 2026 | Klee Justin B. | director, officer: Co-Chief Executive Officer | Sell | 7,715 | $11.09 | $85.6K | 3,317,586 |
| Jan 6, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 7,715 | $11.09 | $85.6K | 0 |
| Jan 6, 2026 | FRATES JAMES M | Chief Financial Officer | Sell | 3,326 | $11.11 | $37.0K | 0 |
| Dec 1, 2025 | Bedrosian Camille L | Chief Medical Officer | Sell | 6,580 | $14.35 | $94.4K | 0 |
| Sep 30, 2025 | Bedrosian Camille L | Chief Medical Officer | Sell | 12,039 | $14.58 | $175.5K | 0 |
| Sep 30, 2025 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 29,933 | $14.35 | $429.5K | 0 |
| Sep 30, 2025 | FRATES JAMES M | Chief Financial Officer | Sell | 10,558 | $14.65 | $154.7K | 0 |
| Sep 30, 2025 | Klee Justin B. | Co-Chief Executive Officer | Sell | 29,975 | $14.38 | $431.0K | 0 |
| Sep 30, 2025 | Mazzariello Gina | Chief Legal Officer | Sell | 8,828 | $14.58 | $128.7K | 0 |
| Aug 12, 2025 | Mazzariello Gina | Chief Legal Officer | Sell | 30,000 | $8.20 | $246.1K | 0 |
| Mar 31, 2025 | Bedrosian Camille L | Chief Medical Officer | Sell | 12,425 | $3.47 | $43.1K | 0 |
| Mar 31, 2025 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 21,490 | $3.47 | $74.5K | 0 |
| Mar 31, 2025 | FRATES JAMES M | Chief Financial Officer | Sell | 10,896 | $3.47 | $37.8K | 0 |
| Mar 31, 2025 | Klee Justin B. | Co-Chief Executive Officer | Sell | 21,490 | $3.46 | $74.5K | 0 |
| Mar 31, 2025 | Mazzariello Gina | Chief Legal Officer | Sell | 9,192 | $3.48 | $32.0K | 0 |
| Mar 3, 2025 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 4,595 | $3.17 | $14.5K | 0 |
| Mar 3, 2025 | Klee Justin B. | Co-Chief Executive Officer | Sell | 4,595 | $3.15 | $14.5K | 0 |
| Mar 3, 2025 | Mazzariello Gina | Chief Legal Officer | Sell | 1,611 | $3.12 | $5.0K | 0 |
| Feb 24, 2025 | Mazzariello Gina | Chief Legal Officer | Sell | 4,169 | $3.15 | $13.1K | 0 |
| Feb 3, 2025 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 11,851 | $3.47 | $41.1K | 0 |
| Feb 3, 2025 | Klee Justin B. | Co-Chief Executive Officer | Sell | 11,855 | $3.47 | $41.1K | 0 |
| Feb 3, 2025 | Mazzariello Gina | Chief Legal Officer | Sell | 3,678 | $3.49 | $12.8K | 0 |
| Jan 6, 2025 | Cohen Joshua B | Co-Chief Executive Officer | Sell | 7,471 | $4.05 | $30.2K | 0 |
| Jan 6, 2025 | Klee Justin B. | Co-Chief Executive Officer | Sell | 7,471 | $4.04 | $30.2K | 0 |
| Dec 2, 2024 | Bedrosian Camille L | Chief Medical Officer | Sell | 5,421 | $5.54 | $30.0K | 0 |
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